Tuning charge density of chimeric antigen receptor optimizes tonic signaling and CAR-T cell fitness | Cell Research
Tonic Signaling and Its Effects on Lymphopoiesis of CAR-Armed Hematopoietic Stem and Progenitor Cells
CAR-T design: Elements and their synergistic function - eBioMedicine
Tonic 4-1BB Costimulation in Chimeric Antigen Receptors Impedes T Cell Survival and Is Vector-Dependent - ScienceDirect
New mechanism in preventing CAR-T cell exhaustion
Tuning charge density of chimeric antigen receptor optimizes tonic signaling and CAR-T cell fitness | Cell Research
Scientists in the SLST and collaborators develop a CAR rational design platform
Tonic Signaling and Its Effects on Lymphopoiesis of CAR-Armed Hematopoietic Stem and Progenitor Cells
Context matters in CAR T cell tonic signaling | Nature Medicine
Rational Tuning of CAR Tonic Signaling Yields Superior T-Cell Therapy for Cancer | bioRxiv
Tonic 4-1BB Costimulation in Chimeric Antigen Receptors Impedes T Cell Survival and Is Vector-Dependent - ScienceDirect
TCR-like platform – Lentistem Biotech
Rational Tuning of CAR Tonic Signaling Yields Superior T-Cell Therapy for Cancer | bioRxiv
Physiological lentiviral vectors for the generation of improved CAR-T cells: Molecular Therapy - Oncolytics
Tonic Signals: Why Do Lymphocytes Bother?
Tonic Signals: Why Do Lymphocytes Bother?
Jacob Plieth on X: "Max Mamonkin (Baylor) suggesting CAR clustering as a reason for tonic signalling (i.e., signal in absence of antigen) #CARTCR https://t.co/Lmwld40Iue" / X
Multi-antigen-targeted chimeric antigen receptor T cells for cancer therapy | Journal of Hematology & Oncology | Full Text